Careers. Metab. Stopping finasteride treatment can cause post-finasteride syndrome. -, Baig M.S., Kolasa-Wolosiuk A., Pilutin A., Safranow K., Baranowska-Bosiacka I., Kabat-Koperska J., Wiszniewska B. Finasteride-induced inhibition of 5alpha-reductase type 2 could lead to kidney damage-animal, experimental study. To give you a bit of background, I'm a 34 year old male whose sexual function was utterly destroyed by finasteride/Propecia. Im talking about the physical inability to have erections and sex drive". official website and that any information you provide is encrypted And yeah I know hackstasis, looks to be a much better community and forum than propeciahelp without fascist mods. .c_dVyWK3BXRxSN3ULLJ_t{border-radius:4px 4px 0 0;height:34px;left:0;position:absolute;right:0;top:0}._1OQL3FCA9BfgI57ghHHgV3{-ms-flex-align:center;align-items:center;display:-ms-flexbox;display:flex;-ms-flex-pack:start;justify-content:flex-start;margin-top:32px}._1OQL3FCA9BfgI57ghHHgV3 ._33jgwegeMTJ-FJaaHMeOjV{border-radius:9001px;height:32px;width:32px}._1OQL3FCA9BfgI57ghHHgV3 ._1wQQNkVR4qNpQCzA19X4B6{height:16px;margin-left:8px;width:200px}._39IvqNe6cqNVXcMFxFWFxx{display:-ms-flexbox;display:flex;margin:12px 0}._39IvqNe6cqNVXcMFxFWFxx ._29TSdL_ZMpyzfQ_bfdcBSc{-ms-flex:1;flex:1}._39IvqNe6cqNVXcMFxFWFxx .JEV9fXVlt_7DgH-zLepBH{height:18px;width:50px}._39IvqNe6cqNVXcMFxFWFxx ._3YCOmnWpGeRBW_Psd5WMPR{height:12px;margin-top:4px;width:60px}._2iO5zt81CSiYhWRF9WylyN{height:18px;margin-bottom:4px}._2iO5zt81CSiYhWRF9WylyN._2E9u5XvlGwlpnzki78vasG{width:230px}._2iO5zt81CSiYhWRF9WylyN.fDElwzn43eJToKzSCkejE{width:100%}._2iO5zt81CSiYhWRF9WylyN._2kNB7LAYYqYdyS85f8pqfi{width:250px}._2iO5zt81CSiYhWRF9WylyN._1XmngqAPKZO_1lDBwcQrR7{width:120px}._3XbVvl-zJDbcDeEdSgxV4_{border-radius:4px;height:32px;margin-top:16px;width:100%}._2hgXdc8jVQaXYAXvnqEyED{animation:_3XkHjK4wMgxtjzC1TvoXrb 1.5s ease infinite;background:linear-gradient(90deg,var(--newCommunityTheme-field),var(--newCommunityTheme-inactive),var(--newCommunityTheme-field));background-size:200%}._1KWSZXqSM_BLhBzkPyJFGR{background-color:var(--newCommunityTheme-widgetColors-sidebarWidgetBackgroundColor);border-radius:4px;padding:12px;position:relative;width:auto} What is infertility? Check his posts and look at the reasons. 2016;93:9. Do you and your partner want to have a baby? As here reported, these observations are mainly based on self-reporting of the symptomatology by the patients and few clinical studies have been performed so far. You can't get worse than living with no dick dude. A mod answered and I answered the guy in a normal way, but they deleted my reply and blocked my account. They have some pretty smart people and are open to trying about anything, and isnt as negative as the other forum. Therefore, I cut the pills in half (2.5mg) and toss the other half. Very controversial topic in this forum. The article stated proviron was the best potential cure in his opinion. There was this guy on propecia help called JustQuitDut who was a complete psycho, who thought that taking TRT with estrogen blockers would somehow solve it. Proviron saved my life. I think it took 6 months before i felt ready to meet a girl again. The .gov means its official. Even my genitals began to grow normal size again. Answer: Hormonal optimization while on finesteride there are many options including peptides, and HCG as well as clomid/arimidex. Accessed Oct. 28, 2021. Write down any symptoms you're experiencing, including any that might seem unrelated to the reason for which you scheduled the appointment. WebNeurogenesis was found to be reversed to normal 35 days after the last finasteride injection in male mice. Post-finasteride syndrome: a surmountable challenge for clinicians. ._1sDtEhccxFpHDn2RUhxmSq{font-family:Noto Sans,Arial,sans-serif;font-size:14px;font-weight:400;line-height:18px;display:-ms-flexbox;display:flex;-ms-flex-flow:row nowrap;flex-flow:row nowrap}._1d4NeAxWOiy0JPz7aXRI64{color:var(--newCommunityTheme-metaText)}.icon._3tMM22A0evCEmrIk-8z4zO{margin:-2px 8px 0 0} Mods are always talking about the survey too, I said a survey wont cure us and we could be be waiting for 10 years if we dont do anything. After a few days I starting liking women again and became sexually from frustrated. In addition, molecular mechanisms and/or genetic determinants behind such adverse effects have been poorly explored both in patients and animal models. Fertil Steril. https://www.hairlosstalk.com/interact/threads/how-i-cured-my-problem-with-post-finasteride-syndrome.125634/. Instead of having a discussion, nope banned. .FIYolDqalszTnjjNfThfT{max-width:256px;white-space:normal;text-align:center} decreased libido * (sex drive) erectile dysfunction *. Gained 25 pounds of mostly muscle. Amedical opinion on this procedure would be important, because we do not have scientific evidence about HCG and PFS, but it would already be a start. Nature Reviews Urology. That is 250IU, not a typo so youll mix your 5000iu HCG with 5CC water and take 1/4 CC intramuscular three times a week using an insulin needle Have you heard about it? /*# sourceMappingURL=https://www.redditstatic.com/desktop2x/chunkCSS/TopicLinksContainer.3b33fc17a17cec1345d4_.css.map*/I had no libido, my erections were weak and i couldnt sustain them. Accessed Sept. 15, 2016. If you have retrograde ejaculation, you'll likely need treatment to get your female partner pregnant. Mild side effects that have been reported with finasteride include: ejaculation problems. I am not aware of the use of Human Growth Hormone in the treatment for Post Finasteride Syndrome. Btw, something weird happening on propeciahelp forums. Will my partner and I likely need to use assisted reproductive technology, such as intrauterine insemination, to achieve pregnancy? The symptoms of PFS start to subside within four to eight months after discontinuing the medicine. If medication doesn't allow you to ejaculate semen, you will likely need infertility procedures known as assisted reproductive technology to get your partner pregnant. Your doctor will ask you questions about your health and symptoms. government site. It is available as a generic. After taking 50mg of Proviron I got my first erection in years. http://www.resolve.org/about-infertility/what-is-infertility/frequently-asked-questions-about-infertility.html. Best, Dr. Emer. J Sex Med. Mesterolone (Proviron) is one of the best compounds that can be used for treating Post Finasteride Syndrome in my opinion. Is Post Finasteride Syndrome Real? All rights reserved. Q. I have heard that finasteride, which I take for my prostate problem, can cause permanent impotence. This site complies with the HONcode standard for trustworthy health information: verify here. And quite frankly, if you think big pharma doesn't have millions and millions of dollars wrapped up in trying to cover up just how severely finasteride has destroyed mens' lives, you're fooling yourself. Do they benefit from people who have pfs so their foundation can continue and ask for more donations? This condition, termed post-finasteride syndrome (PFS) is characterized by sexual side effects (i.e., low libido, erectile dysfunction, decreased arousal and difficulty in achieving orgasm), depression, anxiety and cognitive complaints that are still present despite drug withdrawal. In some people with PFS, DHT might be normal, but testosterone and cortisol low and estrogen and prolactin high. Traish AM, Melcangi RC, Bortolato M, Garcia-Segura LM, Zitzmann M. Rev Endocr Metab Disord. I suspect that 2 mg would be adequate, but if my doc prescribes two 1mg pills per day, the insurance company wont pay for it because the 1mg pill is only approved for hair loss treatment. Fertility and Sterility. Archivio Istituzionale della Ricerca Unimi, NCI CPTC Antibody Characterization Program, Agis-Balboa R.C., Guidotti A., Pinna G. 5alpha-reductase type I expression is downregulated in the prefrontal cortex/Brodmann's area 9 (BA9) of depressed patients. Accessed Oct. 28, 2021. Is there a generic alternative to the medicine you're prescribing me? 2018;120:143149. Yeah, that guy's comment history is really puzzling: When i dared visit PFS forums, the most miserable users there were still in a better state than me. But it is a risk men should discuss with their doctor prior to starting finasteride. Your doctor might ask: Mayo Clinic does not endorse companies or products. Urology. I guess that never happened. A community dedicated to people suffering long term effects after taking 5-ar inhibitors such as Propecia/Finasteride, or for people who wish to know more about the constellation of symptoms commonly known as Post Finasteride Syndrome. Anejaculation and retrograde ejaculation. However, the side effects of a medication usually go away when you stop taking it. PLUS, the latest news on medical advances and breakthroughs from Harvard Medical School experts. The common denominator in how I feel is Tribulus, period, end of sentence. You're right. Plentiful in opinions, short on facts. Traish AM, Hassani J, Guay AT, Zitzmann M, Hansen ML. Respectfully, I don't care what the article says. Now I can happily say that I no longer have any problem, strong erection all day and all night. Studies show it can help slow or reverse the process of hair loss. I feel like I have my life back. 2022 Jul 27;15(8):930. doi: 10.3390/ph15080930. Around 8 months and i was pretty much recovered. Understanding all of your options and communicating with your doctor and partner can help. Brain fog. Stopping finasteride treatment can cause post-finasteride syndrome. This may result in side effects such as memory problems or sexual dysfunction (problems that affect the desire for or ability to have sex). Post-finasteride syndrome wasnt reported in clinical studies, but it has been reported since the drug was approved. After a bit over a week I decreased the dose to 10mg before bedtime and none in the afternoon. I dunno, I dont get it. Their attitude is 100% there is no cure, it wont get better, nothing works, anything that does work doesnt work long term, and thats just how it is. Please visit the wiki for published research, symptoms, and more. https://www.amazon.com/reviews/R3OGTPUQ1CP005. I need to get back over there and check it out I guess. Liu L, Zhao S, Li F, Li E, Kang R, Luo L, Luo J, Wan S, Zhao Z. J Sex Med. Crazy. No active 34 year old man should have to be having ED discussions with his physician. I have the desire for sex and intimacy but my brain simply wont communicate with my penis when its time for intercourse. Even Viagra wouldnt get me hard. You're likely to start by seeing your family doctor. This is to be expected because you are messing with a hormone (DHT) that is very important for sexual function. Do you have cloudy urine after an orgasm? While they're often an effective treatment for retrograde ejaculation, medications can cause side effects or adverse reactions with other medications. Authors received funding from the Post-Finasteride Foundation in order to study PFS symptomatology of patients and in experimental models. I just decided to get back on gear after a year off + dutasteride during that time. I also tried testosterone treatment but it had almost no effect regardless of dosage. My life is finally back. ._1LHxa-yaHJwrPK8kuyv_Y4{width:100%}._1LHxa-yaHJwrPK8kuyv_Y4:hover ._31L3r0EWsU0weoMZvEJcUA{display:none}._1LHxa-yaHJwrPK8kuyv_Y4 ._31L3r0EWsU0weoMZvEJcUA,._1LHxa-yaHJwrPK8kuyv_Y4:hover ._11Zy7Yp4S1ZArNqhUQ0jZW{display:block}._1LHxa-yaHJwrPK8kuyv_Y4 ._11Zy7Yp4S1ZArNqhUQ0jZW{display:none} Sometimes, more-advanced assisted reproductive techniques are needed. Ive personally recovered from pfs but what worked for me may not work for you as each of our bodies react differently to this condition depending on individuals factors. Do you ever ejaculate semen when you have an orgasm, or do you have a dry orgasm every time? If we cant discuss potential cures then that forum is completely worthless and I start to doubt their real intentions. The results have been amazing and far too great to chalk it up to just being a placebo. ._3oeM4kc-2-4z-A0RTQLg0I{display:-ms-flexbox;display:flex;-ms-flex-pack:justify;justify-content:space-between} Create an account to follow your favorite communities and start taking part in conversations. This stuff WORKS. If your doctor thinks drugs you are taking might be affecting your ability to ejaculate normally, he or she might have you stop taking them for a period of time. If youre experiencing a medical issue, please contact a healthcare professional or dial 911 immediately. Get helpful tips and guidance for everything from fighting inflammation to finding the best diets for weight lossfrom exercises to build a stronger core to advice on treating cataracts. https://forum.propeciahelp.com/t/i-think-im-healed-after-six-year-nightmare/35477. Unable to load your collection due to an error, Unable to load your delegates due to an error. https://old.reddit.com/r/PostFinSyndrome/comments/ogcsjc/i_recovered_from_pfs_it_is_possible/. WebPost-finasteride syndrome (PFS) is a constellation of serious adverse side effects manifested in clinical symptoms that develop and persist in patients during and/or after discontinuing finasteride treatment in men with pattern hair loss (androgenetic alopecia) or Ohl DA, et al. Midodrine, a medicine that constricts blood vessels. TRT so thats why I went down this rabbit hole. there are many options including peptides, and HCG as well as clomid/arimidex. Proton-pump inhibitors: Should I still be taking this medication? Althof HE, et al. https://www.jasonemermd.com/cosmetic-dermatology/regenerative-medicine/hormonal-optimization/. ._1x9diBHPBP-hL1JiwUwJ5J{font-size:14px;font-weight:500;line-height:18px;color:#ff585b;padding-left:3px;padding-right:24px}._2B0OHMLKb9TXNdd9g5Ere-,._1xKxnscCn2PjBiXhorZef4{height:16px;padding-right:4px;vertical-align:top}.icon._1LLqoNXrOsaIkMtOuTBmO5{height:20px;vertical-align:middle;padding-right:8px}.QB2Yrr8uihZVRhvwrKuMS{height:18px;padding-right:8px;vertical-align:top}._3w_KK8BUvCMkCPWZVsZQn0{font-size:14px;font-weight:500;line-height:18px;color:var(--newCommunityTheme-actionIcon)}._3w_KK8BUvCMkCPWZVsZQn0 ._1LLqoNXrOsaIkMtOuTBmO5,._3w_KK8BUvCMkCPWZVsZQn0 ._2B0OHMLKb9TXNdd9g5Ere-,._3w_KK8BUvCMkCPWZVsZQn0 ._1xKxnscCn2PjBiXhorZef4,._3w_KK8BUvCMkCPWZVsZQn0 .QB2Yrr8uihZVRhvwrKuMS{fill:var(--newCommunityTheme-actionIcon)} A review of the FAERS data on 5-alpha reductase inhibitors: implications for postfinasteride syndrome. Effect of 5-Reductase Inhibitors on Sexual Function: A Meta-Analysis and Systematic Review of Randomized Controlled Trials. This site needs JavaScript to work properly. Alterations in orgasm are linked with lower emotional and physical satisfaction, which might lead to stress for you and your partner. Retrograde ejaculation typically doesn't require treatment unless it interferes with fertility. ._2cHgYGbfV9EZMSThqLt2tx{margin-bottom:16px;border-radius:4px}._3Q7WCNdCi77r0_CKPoDSFY{width:75%;height:24px}._2wgLWvNKnhoJX3DUVT_3F-,._3Q7WCNdCi77r0_CKPoDSFY{background:var(--newCommunityTheme-field);background-size:200%;margin-bottom:16px;border-radius:4px}._2wgLWvNKnhoJX3DUVT_3F-{width:100%;height:46px} Are there other possible causes for my symptoms or condition? Samplaski MK, et al. Sexual side effects: Loss of libido, impotence, testicular pain, testicle shrinkage, minor Peyronies (up to 10 degrees), penis pain, watery semen, Mental: Anxiety, insomnia, cognitive issues / brain fog. Shift work can harm sleep and health: What helps? Diviccaro S, Giatti S, Cioffi L, Falvo E, Herian M, Caruso D, Melcangi RC. I read the thing on Healthline where it says it doesn't raise testosterone in humans. Post Finasteride Syndrome can be manually corrected by interpreting blood work and implementing an appropriate lifestyle and/or pharmacological protocol. Federal government websites often end in .gov or .mil. I know it's been a LONG time and also want to tell everyone that I'm cured from PFS great news. And posted the article and some cliffs about his solution. doi: 10.1210/jc.2016-2726. Its easy to point to a little blue pill you took 10 years ago than to look for other causes. Speaking of which the proviron I ordered over a year ago randomly came in the mail the other day, haha. For what it's worth, here's a couple similar success stories involving numbness, but from PSSD instead of PFS: Testosterone along with initial estrogen management , completely cured my pssd, everything from numbness, to hard on quality , no morning wood, to actually having sexual desires again. Ive been doing this for over 2 years and have ZERO sexual side effects from the drug. Advise Me with Something Good I Can Do to my Hair. His article with all the studies hes referencing: Post Finasteride Syndrome can be manually corrected by interpreting blood work and implementing an appropriate lifestyle and/or pharmacological protocol. WebA deterioration in the quality of life in affected individuals does not justify use of the drug. Health Alerts from Harvard Medical School. .s5ap8yh1b4ZfwxvHizW3f{color:var(--newCommunityTheme-metaText);padding-top:5px}.s5ap8yh1b4ZfwxvHizW3f._19JhaP1slDQqu2XgT3vVS0{color:#ea0027} Next steps is likely getting a Hey there, Is my condition likely temporary or chronic? Maybe if theyre lucky in 10 years. The drug reduces a testosterone-related hormone in certain tissues, including skin and the prostate gland. Most men eventually develop some type of prostate problem, and when they do there are usually no easy solutions. The dosage needs to be low and steady, do not increase or add a day thinking more is better. I have had a recent report of a man who went on Human Growth Hormone and reversed his post finasteride syndrome sexual dysfunction. .Rd5g7JmL4Fdk-aZi1-U_V{transition:all .1s linear 0s}._2TMXtA984ePtHXMkOpHNQm{font-size:16px;font-weight:500;line-height:20px;margin-bottom:4px}.CneW1mCG4WJXxJbZl5tzH{border-top:1px solid var(--newRedditTheme-line);margin-top:16px;padding-top:16px}._11ARF4IQO4h3HeKPpPg0xb{transition:all .1s linear 0s;display:none;fill:var(--newCommunityTheme-button);height:16px;width:16px;vertical-align:middle;margin-bottom:2px;margin-left:4px;cursor:pointer}._1I3N-uBrbZH-ywcmCnwv_B:hover ._11ARF4IQO4h3HeKPpPg0xb{display:inline-block}._2IvhQwkgv_7K0Q3R0695Cs{border-radius:4px;border:1px solid var(--newCommunityTheme-line)}._2IvhQwkgv_7K0Q3R0695Cs:focus{outline:none}._1I3N-uBrbZH-ywcmCnwv_B{transition:all .1s linear 0s;border-radius:4px;border:1px solid var(--newCommunityTheme-line)}._1I3N-uBrbZH-ywcmCnwv_B:focus{outline:none}._1I3N-uBrbZH-ywcmCnwv_B.IeceazVNz_gGZfKXub0ak,._1I3N-uBrbZH-ywcmCnwv_B:hover{border:1px solid var(--newCommunityTheme-button)}._35hmSCjPO8OEezK36eUXpk._35hmSCjPO8OEezK36eUXpk._35hmSCjPO8OEezK36eUXpk{margin-top:25px;left:-9px}._3aEIeAgUy9VfJyRPljMNJP._3aEIeAgUy9VfJyRPljMNJP._3aEIeAgUy9VfJyRPljMNJP,._3aEIeAgUy9VfJyRPljMNJP._3aEIeAgUy9VfJyRPljMNJP._3aEIeAgUy9VfJyRPljMNJP:focus-within,._3aEIeAgUy9VfJyRPljMNJP._3aEIeAgUy9VfJyRPljMNJP._3aEIeAgUy9VfJyRPljMNJP:hover{transition:all .1s linear 0s;border:none;padding:8px 8px 0}._25yWxLGH4C6j26OKFx8kD5{display:inline}._2YsVWIEj0doZMxreeY6iDG{font-size:12px;font-weight:400;line-height:16px;color:var(--newCommunityTheme-metaText);display:-ms-flexbox;display:flex;padding:4px 6px}._1hFCAcL4_gkyWN0KM96zgg{color:var(--newCommunityTheme-button);margin-right:8px;margin-left:auto;color:var(--newCommunityTheme-errorText)}._1hFCAcL4_gkyWN0KM96zgg,._1dF0IdghIrnqkJiUxfswxd{font-size:12px;font-weight:700;line-height:16px;cursor:pointer;-ms-flex-item-align:end;align-self:flex-end;-webkit-user-select:none;-ms-user-select:none;user-select:none}._1dF0IdghIrnqkJiUxfswxd{color:var(--newCommunityTheme-button)}._3VGrhUu842I3acqBMCoSAq{font-weight:700;color:#ff4500;text-transform:uppercase;margin-right:4px}._3VGrhUu842I3acqBMCoSAq,.edyFgPHILhf5OLH2vk-tk{font-size:12px;line-height:16px}.edyFgPHILhf5OLH2vk-tk{font-weight:400;-ms-flex-preferred-size:100%;flex-basis:100%;margin-bottom:4px;color:var(--newCommunityTheme-metaText)}._19lMIGqzfTPVY3ssqTiZSX._19lMIGqzfTPVY3ssqTiZSX._19lMIGqzfTPVY3ssqTiZSX{margin-top:6px}._19lMIGqzfTPVY3ssqTiZSX._19lMIGqzfTPVY3ssqTiZSX._19lMIGqzfTPVY3ssqTiZSX._3MAHaXXXXi9Xrmc_oMPTdP{margin-top:4px} Or at the very least allow people to post ideas. I recovered and I hope all of you suffering from PFS recover too. doi: 10.1177/0960327119842195. For details, see text. For details, see text., Side effects of treatment with 5 alpha-reductase inhibitors in experimental models. Adverse side effects of 5-reductase inhibitors therapy: persistent diminished libido and erectile dysfunction and depression in a subset of patients. Note that prior to this protocol I tried injectable Test enanthate, Masteron, proviron and hcg which made my condition even worse. Here's some information to help you get ready for your appointment, and what to expect from your doctor. No energy. I has numbness also. Thanks for visiting. 150mg/ day transdermal Testosterone gel applied to scrotum - 50mg/ day DHT gel applied to inner forearms and penis - 50mg oral pregnenolone/25mg DHEA daily, https://old.reddit.com/r/FinasterideSyndrome/comments/u1svwo/has_anyone_else_recovered_from_watery_semen_and/i4eg1it/?context=999. 2022 Oct 26;12(11):1567. doi: 10.3390/biom12111567. Please enable it to take advantage of the complete set of features! Gut Inflammation Induced by Finasteride Withdrawal: Therapeutic Effect of Allopregnanolone in Adult Male Rats. ._3Z6MIaeww5ZxzFqWHAEUxa{margin-top:8px}._3Z6MIaeww5ZxzFqWHAEUxa ._3EpRuHW1VpLFcj-lugsvP_{color:inherit}._3Z6MIaeww5ZxzFqWHAEUxa svg._31U86fGhtxsxdGmOUf3KOM{color:inherit;fill:inherit;padding-right:8px}._3Z6MIaeww5ZxzFqWHAEUxa ._2mk9m3mkUAeEGtGQLNCVsJ{font-family:Noto Sans,Arial,sans-serif;font-size:14px;font-weight:400;line-height:18px;color:inherit}
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